Eating regimen sort can enhance doubtlessly dangerous gasoline within the intestine

Printed in Scientific Vitamin, researchers from the College of Minnesota Medical College appeared on the manufacturing of colonic hydrogen sulfide—a poisonous gasoline within the physique that smells like rotten eggs—in folks in response to animal- and plant-based food regimen interventions.

“Though the function of hydrogen sulfide has lengthy been a topic of nice curiosity within the pathogenesis of a number of essential ailments—similar to ulcerative colitis, colon most cancers, and weight problems—previous investigations haven’t been capable of hyperlink dietary knowledge, microbiome characterization and precise hydrogen sulfide manufacturing,” stated Alexander Khoruts, MD, a gastroenterologist within the U of M Medical College and M Well being Fairview. “That is what now we have accomplished right here.”

From a human cohort, the examine helps the final speculation that hydrogen sulfide produced by the intestine microbiota will increase with an animal-based food regimen. Nonetheless, the outcomes additionally instructed the existence of intestine microbiome enterotypes that reply differentially and even paradoxically to totally different dietary enter.

The examine discovered that:

• Within the majority of individuals, a plant-based food regimen resulted in a decrease hydrogen sulfide manufacturing in comparison with an animal-based (i.e., western) food regimen.
• As anticipated, a plant-based food regimen contained extra fiber, whereas an animal-based food regimen contained extra protein.
• In some people, plant-based diets didn’t decrease hydrogen sulfide manufacturing and even led to some will increase in it.
• Preliminary outcomes instructed the existence of various compositions of intestine microbiota (enterotypes) that correlate with differential responsiveness to food regimen by way of hydrogen sulfide manufacturing.

“The examine was according to the final understanding that common consumption of fiber-containing meals is useful to intestine well being,” stated Dr. Levi Teigen, a diet researcher within the Division of Gastroenterology within the U of M Medical College. “Future analyses of the intestine microbiome might assist to individualize diet interventions.”