Popular Malaysian soup can cause liver damage when mixed with medication
The impact of 4 totally different bak kut teh formulations on HepG2 cells after 48 h of publicity. A Formulation #1 confirmed vital toxicity earlier than dilution (p = 0.023), however demonstrated no vital toxicity as soon as diluted (p > 0.05). B Formulation #2 demonstrated vital toxicity with no dilution issue (p = 0.009), however none as soon as diluted (p > 0.05). C Bak kut teh Formulation #3 confirmed related toxicity when undiluted (p  0.05). D Formulation #4 was proven to be considerably poisonous undiluted (p Forensic Science, Medication and Pathology (2022). DOI: 10.1007/s12024-022-00490-5

Researchers from the College of Adelaide have discovered {that a} well-liked soup, bak kut teh, has the potential to trigger liver failure by clashing with prescription treatment.

“Our staff studied the recipes of 4 regionally bought packet mixes of bak kut teh, in any other case often known as meat bone tea,” stated Professor Roger Byard, George Richard Marks Chair of Pathology on the College of Adelaide. “When blended with liver cells, the components killed as much as 83% in a single concentrated soup components.

“Folks have been warned for a while that natural medicines and therapies could have dangerous unintended effects that may embody vital liver harm. In uncommon instances this has required transplantation and even led to loss of life.

“For the primary time, a laboratory research by the College of Adelaide has proven that meals containing herbs, such because the soup bak kut teh, may additionally be poisonous to liver cells.

“Folks with underlying liver illness or who’re taking prescription medicines must be warned of this potential aspect impact. All such preparations ought to embody correct labeling of the components till additional research will be undertaken to establish the particular natural substances which can be poisonous. Having the soup at house or at a restaurant could trigger harm to the liver.

“If surprising liver harm is encountered at post-mortem, data on potential current ingestion of natural meals preparations must be sought, as routine toxicology screening is not going to establish the lively elements. Liver harm could due to this fact be triggered not solely by natural medicines, however probably natural merchandise contained in meals.”

The components of every of the soups diverse significantly from one label to a different.

They included:

  • Formulation one: Dried hawthorn
  • Formulation two: Goji berries, ginseng, bark, and dried mushrooms
  • Formulation three: Polygonatum odoratum, ligusticum chuanxiong, codonopsis pilosula, cinnamomum cassia, angelica sinensis, illicium verum, piper nigrum, and Eugenia caryophyllata
  • Formulation 4: Spices, pepper and salt

All formulations of bak kut teh demonstrated vital ranges of toxicity.

The outcomes of the assessments have been revealed within the journal Forensic Science, Medication and Pathology.


Highlighting the dangers posed by natural medicines to the Australian group


Extra data:
Susan M. Britza et al, May natural soup be a doubtlessly unrecognized reason for hepatotoxicity at post-mortem?, Forensic Science, Medication and Pathology (2022). DOI: 10.1007/s12024-022-00490-5

Quotation:
Widespread Malaysian soup could cause liver harm when blended with treatment (2022, July 12)
retrieved 12 July 2022
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