Researchers from the College at Buffalo performed a research of practically 80,000 postmenopausal girls within the U.S. to find out whether or not caffeine consumption from espresso and tea has any affiliation with invasive breast most cancers.
The typical age when U.S. girls attain menopause, 51, additionally occurs to coincide with the age group—50- to 64-year-olds—that has the best reported caffeine consumption. Along with that, the common age of breast most cancers analysis within the U.S. is 62.
This overlap of age at menopause, age at analysis of breast most cancers and age with excessive caffeine consumption gave better weight to the significance of clarifying whether or not caffeine consumption impacts breast most cancers danger in postmenopausal girls.
It doesn’t, in line with the UB researchers’ findings, printed in August within the Worldwide Journal of Most cancers.
“From our literature evaluate, many research have discovered important associations between espresso and/or tea consumption and decreased breast most cancers incidence whereas just a few research have reported elevated danger. Our research, nonetheless, discovered no affiliation,” mentioned research first creator Christina KH Zheng, who labored on the research whereas finishing her grasp’s in epidemiology at UB. She is now a surgical resident within the MedStar Baltimore common surgical procedure program.
“About 85% of People drink not less than one caffeinated beverage a day. It will be significant for the general public to know whether or not consumption of caffeinated drinks has helpful or dangerous results on breast most cancers, the commonest kind of most cancers and second-leading reason behind most cancers demise for U.S. girls,” mentioned Lina Mu, MD, Ph.D., the research’s senior creator, who’s an affiliate professor of epidemiology and environmental well being at UB.
“The overlap of age at analysis of breast most cancers and age with excessive consumption of caffeine, and the inconsistent findings from earlier research motivated us to check whether or not this way of life issue may have an effect on breast most cancers danger in postmenopausal girls,” mentioned Kexin Zhu, a research co-first creator and epidemiology Ph.D. pupil in UB’s Faculty of Public Well being and Well being Professions.
Researchers checked out a pattern of 79,871 contributors within the Ladies’s Well being Initiative Observational Research. Contributors have for many years now accomplished yearly well being questionnaires that assist researchers be taught extra about weight loss plan and train habits, in addition to illness, and any doable linkages.
After a median follow-up of 16 years, there have been 4,719 circumstances of invasive breast most cancers recognized.
At first look, girls who reported ingesting two to a few cups of caffeinated espresso per day had a 12% increased danger of invasive breast most cancers in comparison with non-drinkers. However that affiliation was not statistically important after adjusting for way of life components, reminiscent of smoking and alcohol consumption.
“Seeing null outcomes after adjusting for way of life, demographic and reproductive components informs us of the complexity that’s the relationship between caffeine consumption and invasive breast most cancers danger,” Zheng mentioned.
“Some way of life components, like ingesting alcohol and bodily exercise, may be related to each espresso consumption and breast most cancers danger,” Zhu defined. “Due to this fact, they may confound the preliminary constructive associations. After we took the life-style components under consideration, the outcomes recommended that common espresso ingesting may not have an effect on invasive breast most cancers danger.”
The danger of invasive breast most cancers was even increased—22%—for ladies who reported ingesting two to a few cups of decaffeinated espresso every day. It was barely decrease when adjusted for way of life variables (smoking historical past, alcohol consumption, bodily exercise, and many others.), and the affiliation was not statistically important when additional accounting for reproductive variables reminiscent of household historical past of breast most cancers and variety of kids
The researchers had been unable to find out if the elevated danger is because of the decaffeinated nature of the espresso, the quantity consumed, or one other issue distinctive to this inhabitants that was not accounted for within the research.
The researchers didn’t observe a big affiliation between total tea consumption and invasive breast most cancers. Further analysis must be performed with the intention to perceive whether or not various kinds of teas have completely different results on breast most cancers danger, Zhu mentioned.
Kan Hong Zheng et al, Caffeine consumption from espresso and tea and invasive breast most cancers incidence amongst postmenopausal girls within the Ladies’s Well being Initiative, Worldwide Journal of Most cancers (2021). DOI: 10.1002/ijc.33771
College at Buffalo
Research finds no affiliation between caffeine consumption and invasive breast most cancers danger (2021, September 28)
retrieved 28 September 2021
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