Mounjaro affords a promising solution to handle PMOS signs and assist with weight reduction, enhancing menstrual well being, and life-style adjustments.
In 2023, on the age of 28, I weighed 67 kg, which was common for my peak and construct. At 30, 2.5 years after my marriage, I’ve gained 15 kg. My menstrual cycle is disrupted. For 3 months, I skilled amenorrhea, the medical time period for the absence of menstruation. As a well being and wellness journalist, I knew this was a purple flag and wanted medical intervention. However I used to be not prepared for the medical doctors’ assertion.
My first session
In September 2025, I visited the Indira Gandhi Hospital in Delhi’s Dwarka. I used to be requested to bear two blood checks to verify iron (haemoglobin) and thyroid (TSH) ranges. I additionally underwent a pelvic ultrasound to evaluate whether or not the uterus and ovaries had been functioning usually. The blood experiences had been regular, whereas the ovaries confirmed some cysts. The physician declared, “You have got PCOM”.
What’s PCOM?
About 25% of wholesome ladies have (PCOM) Polycystic Ovarian Morphology, in accordance with the journal Therapeutic Advances in Reproductive Well being. PCOM seems on ultrasound as ovaries with many small follicles. It is a crucial clue for diagnosing Polycystic Ovary Syndrome (PCOS), now known as Polyendocrine Metabolic Ovarian Syndrome (PMOS). Nonetheless, it can’t be used alone for a analysis. “PCOM could also be linked to life-style, weight problems, or it may merely be a standard variation,” stated Dr Ankita Tewatia, Obstetrician and Gynaecologist at Indira Gandhi Hospital.
After seeing my experiences, Dr Tewatia defined, “That is nonetheless not PMOS. Nonetheless, you could scale back weight and make sure life-style adjustments. These are merely hormonal adjustments after your marriage.” I felt relieved and resorted to dietary adjustments like consuming extra high-fiber fruit and veggies. I step by step misplaced 3 kg in 45 days. However my concern continued. I had irregular intervals, and for 2 months, I missed my menstrual cycle. Once I went again to Dr Tewatia for an answer, she instructed I strive Oral Contraceptive Drugs to regularise the cycle.
What are OCPs for PMOS?
Oral contraceptive capsules (OCPs) or contraception capsules are the primary therapy for managing signs of Polyendocrine Metabolic Ovarian Syndrome (PMOS) in ladies who usually are not making an attempt to get pregnant. Though these capsules don’t remedy PMOS, they assist by decreasing male hormone ranges and stabilising the menstrual cycle. However as I stated above, being a journalist, I do know the uncomfortable side effects of OCP capsules, resembling weight acquire, nausea, complications, breast tenderness, and temper swings.
What occurs whenever you take OCP capsules?
Oral Contraceptive Drugs are normally mixed capsules that include estrogen and progestin. I took them day by day for 21 days after which had 7 days off to assist regulate my intervals and decrease androgen ranges. Caught in a scenario the place I used to be determined for my menstrual cycle, I took these OCP capsules. Right here’s what I used to be not warned about: the load regain.
Consuming these capsules led me to realize 5 kgs, bodily fatigue and my temper swings had begun to provide a tricky competitors to my PMS signs. Furthermore, I used to be again to sq. one after I stopped OCPs. My drawback remained the identical: an absent menstrual cycle.
A second opinion
No signal of intervals was an indication that I wanted a second opinion. I approached Dr Saptarshi Bhattacharya, Endocrinologist and Diabetologist at Indraprastha Apollo Hospitals, whom my mother and father have been referring to for 15 years for his or her diabetes and thyroid points.
I booked my appointment in January 2026. After reviewing my experiences, Dr Bhattacharya stated, “You’re borderline overweight. Shedding pounds is essential due to your loved ones historical past of kind 2 diabetes. If PMOS isn’t managed, you’ll develop it. Whether or not it’s life-style, hormones, or OCPs, it’s time to behave. If weight-reduction plan and train don’t work, I’m prescribing Mounjaro (tirzepatide).”
My trustworthy and surprising response
I had been writing about Mounjaro, the GLP-1 drug, however wasn’t ready to be prescribed it personally. Taking a look at my perplexed response, the physician requested me about my household planning. Once I replied that we’re not there but and had no speedy plans, he defined: “Mounjaro hasn’t been examined on pregnant ladies, so it might’t be prescribed to them or anybody planning to conceive.”
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Does Mounjaro helps with PMOS?
Mounjaro (tirzepatide) is usually prescribed off-label for Polyendocrine Metabolic Ovarian Syndrome (PMOS) as a result of it targets two major issues: insulin resistance and weight acquire. Mounjaro is a twin agonist that mimics the intestine hormones GLP-1 and GIP to control blood sugar and urge for food. Its advantages for PMOS embrace decreasing insulin resistance, vital weight reduction, hormonal regulation, restoration of menstrual cycles, and boosting fertility.
Is weight reduction with PMOS simple with Mounjaro?
Once I requested this query, Dr Bhattacharya answered, “Mounjaro (tirzepatide) may be very efficient for weight reduction in individuals with PMOS. It helps by tackling insulin resistance and decreasing urge for food. Regulating blood sugar makes you’re feeling fuller, serving to you eat fewer energy. Nonetheless, to shed extra pounds, it’s necessary to keep up a nutritious diet and life-style moderately than relying solely on remedy.”
My turning level
After I mentioned the whole case with my household and we studied concerning the seemingly uncomfortable side effects of Mounjaro, we determined I give weight reduction a shot the pure means. I’ve corrected my weight-reduction plan and as huge step within the wholesome life-style course, I’ve joined a fitness center regardless of my busy schedule. I chalk out an hour daily earlier than or after my work hours, and I’m surprisingly loving it. I’m following a 6-day-a-week exercise plan.
Look forward to my subsequent story, the place I’ll inform you what the fitness center did to my physique in simply 9 days.
