Mounjaro might assist to shed pounds, however it could additionally have an effect on your bowel actions. Let’s discover out the connection between Mounjaro and constipation.
Mounjaro is without doubt one of the diabetes medicine that may preserve blood sugar below management and likewise assist folks to shed pounds. These two are the important thing advantages of this injectable drugs, however it additionally has potential unwanted side effects on the physique. Constipation is one such well being situation. Utilizing Mounjaro to handle kind diabetes or drop kilos might have an effect in your bowel actions. It may well make your stools tougher, so you could find yourself struggling on the bathroom. Thankfully, there are some things you are able to do to get reduction from constipation.
What’s Mounjaro?
Mounjaro is the model title of tirzepatide, a medication that is available in a pre-filled pen. It’s a blood sugar-lowering medicine that’s usually prescribed to folks with kind 2 diabetes. “This drugs works by activating two receptors referred to as GLP-1 (glucagon-like peptide-1) and GIP (Gastric Inhibitory Polypeptide), which increase the physique’s ranges of incretins (intestine hormones),” shares endocrinologist Dr Sandeep Kharb. It really works by stimulating your physique’s manufacturing of insulin at any time when wanted. It additionally limits the amount of sugar produced by the liver and slows down digestion, serving to in lowering blood sugar ranges.
The US Meals and Drug Administration recommends it to handle blood sugar ranges in adults with kind 2 diabetes, and never for kind 1 diabetes or weight reduction. The beginning dosage is 2.5 mg that must be injected subcutaneously within the stomach, thigh or higher arm as soon as per week. After 4 weeks, the dosage might be elevated to five mg. The utmost dosage of this drugs is 15 mg.
Mounjaro and constipation: A aspect impact of this diabetes drug
In March 2025, the FDA shared that it obtained adversarial occasion studies that could be associated to folks utilizing tirzepatide in doses past what has been accepted by the company. In keeping with the company, folks skilled signs like vomiting, diarrhea, constipation and stomach ache. “Constipation is an anticipated adversarial impact of Mounjaro,” says Dr Kharb.
Right here’s how Mounjaro and constipation could also be linked:
- Decreased intestinal motion: This may also help management your blood sugar and preserve you full for a very long time, however decreased intestinal motion may contribute to constipation.
- Decreased urge for food: There could also be a hyperlink between Mounjaro and constipation, as this medicine can scale back urge for food. “When you don’t eat or drink water a lot, it could result in much less fibre and fluid consumption,” says the skilled. Fibre is a nutrient that helps to bulk up poop and make it simpler to cross. Alternatively, enough fluid consumption is necessary, because it helps to melt stools.
- Adjustments in absorption of fluids: Whereas taking this drugs, water in your stools might get absorbed, leading to firmer, extra difficult-to-pass stools.
Mounjaro and constipation: get reduction?
Mounjaro and constipation could also be linked, however don’t fear, you’ll be able to take easy steps to get reduction. You simply need to give attention to easy life-style changes.
1. Keep hydrated
Make certain to have an enough quantity of water to assist soften your stools and promote common bowel actions. You simply have heard of individuals emphasising on ingesting between 8 and 10 glasses of water every day. Nicely, this wholesome behavior may also help to melt stools and make your bowel actions common.
2. Get transferring
“Constipation might be prevented and handled by common bodily exercise, equivalent to strolling or swimming,” says the skilled. Strolling, particularly after meals, helps digestion by stimulating intestinal exercise. This may also help in stopping sluggish motion within the intestine.
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3. Say sure to fiber
Fiber is not only necessary to handle weight. “Going for a high-fiber weight loss program can improve your stool bulk and enhance bowel regularity,” says the skilled. Together with greens, have kidney beans, chia seeds and prunes for constipation administration, as they’re all wealthy in fibre.
4. Medicines
There are stool softeners that may provide help to get reduction from constipation. A few of the medicines embody magnesium citrate, docusate sodium, magnesium citrate and polyethylene glycol. Checking with a health care provider relating to these medicines and their simply out there kinds is a should.
What are the unwanted side effects of Mounjaro for digestion?
Other than the Mounjaro and constipation connection, it might have an effect on your digestive well being in numerous methods. Different unwanted side effects of Mounjaro for digestion embody:
- Nausea
- Vomiting
- Indigestion
- Diarrhea
“These are usually extra intense whereas beginning the medicine or rising its dosage. Over time, your physique will be capable to adapt. And so, tolerance develops, resulting in a discount in symptom severity,” says Dr Kharb.
Nonetheless, sure meals and drinks can worsen these points. “Oily and spicy meals are likely to irritate the digestive system, prolonging discomfort and triggering acid reflux disease. Additionally, aerated drinks contribute to fuel buildup and acidity, aggravating indigestion,” says the skilled.
Mounjaro long-term unwanted side effects
Whereas there’s a hyperlink between Mounjaro and constipation, taking the medicine to handle kind 2 diabetes and shed pounds might result in extra unwanted side effects. The record contains nausea and acute pancreatitis. It’s best to seek the advice of a health care provider relating to the injectable medicine and dosage.
- It might result in muscle loss, as weight discount impacts fats in addition to muscle mass.
- Acute pancreatitis, a situation that happens when the pancreas will get swollen up and turns into infected in a brief time frame, is a uncommon however documented aspect impact of tirzepatide (Mounjaro), as per analysis revealed in Cureus.
- There’s a chance of gallstones.
Associated FAQs
What’s the finest fibre complement for Mounjaro?
Incorporating entire grains, fruits, greens, and beans into your weight loss program is the easiest way to help your digestive well being. These meals assist by rising fibre consumption and selling common bowel actions. You can too go for a fibre complement like Metamucil, however seek the advice of a health care provider first.
Can you are taking laxatives whereas on Mounjaro?
Laxatives can be utilized to alleviate constipation whereas taking Mounjaro, however they need to solely be taken after consulting a health care provider. Medical steering ensures the suitable kind and dosage, stopping dependency or undesirable unwanted side effects.
